[HTML][HTML] ATP-dependent and ATP-independent roles for the Rad54 chromatin remodeling enzyme during recombinational repair of a DNA double strand break
B Wolner, CL Peterson - Journal of Biological Chemistry, 2005 - ASBMB
The efficient and accurate repair of DNA double strand breaks (DSBs) is critical to cell
survival, and defects in this process can lead to genome instability and cancers. In
eukaryotes, the Rad52 group of proteins dictates the repair of DSBs by the error-free
process of homologous recombination (HR). A critical step in eukaryotic HR is the formation
of the initial Rad51-single-stranded DNA presynaptic nucleoprotein filament. This
presynaptic filament participates in a homology search process that leads to the formation of …
survival, and defects in this process can lead to genome instability and cancers. In
eukaryotes, the Rad52 group of proteins dictates the repair of DSBs by the error-free
process of homologous recombination (HR). A critical step in eukaryotic HR is the formation
of the initial Rad51-single-stranded DNA presynaptic nucleoprotein filament. This
presynaptic filament participates in a homology search process that leads to the formation of …