CD19-targeted CAR T cells in refractory systemic lupus erythematosus
D Mougiakakos, G Krönke, S Völkl… - … England Journal of …, 2021 - Mass Medical Soc
New England Journal of Medicine, 2021•Mass Medical Soc
CAR T Cells for Refractory Systemic Lupus Erythematosus A 20-year-old woman with
refractory SLE with active lupus nephritis (WHO class IIIA), nephrotic syndrome, pericarditis,
pleurisy, rash, arthritis, and a history of Libman–Sacks endocarditis refractory to
conventional immunosuppression had a complete response to CD19-specific chimeric
antigen receptor T cells.
refractory SLE with active lupus nephritis (WHO class IIIA), nephrotic syndrome, pericarditis,
pleurisy, rash, arthritis, and a history of Libman–Sacks endocarditis refractory to
conventional immunosuppression had a complete response to CD19-specific chimeric
antigen receptor T cells.
CAR T Cells for Refractory Systemic Lupus Erythematosus
A 20-year-old woman with refractory SLE with active lupus nephritis (WHO class IIIA), nephrotic syndrome, pericarditis, pleurisy, rash, arthritis, and a history of Libman–Sacks endocarditis refractory to conventional immunosuppression had a complete response to CD19-specific chimeric antigen receptor T cells.
The New England Journal Of Medicine