Dual-histamine receptor blockade with cetirizine-famotidine reduces pulmonary symptoms in COVID-19 patients
RB Hogan Ii, RB Hogan Iii, T Cannon, M Rappai… - Pulmonary …, 2020 - Elsevier
Background The COVID-19 pandemic due to SARS-CoV-2 infection can produce Acute
Respiratory Distress Syndrome as a result of a pulmonary cytokine storm. Antihistamines are
safe and effective treatments for reducing inflammation and cytokine release. Combinations
of Histamine-1 and Histamine-2 receptor antagonists have been effective in urticaria, and
might reduce the histamine-mediated pulmonary cytokine storm in COVID-19. Can a
combination of Histamine-1 and Histamine-2 receptor blockers improve COVID-19 inpatient …
Respiratory Distress Syndrome as a result of a pulmonary cytokine storm. Antihistamines are
safe and effective treatments for reducing inflammation and cytokine release. Combinations
of Histamine-1 and Histamine-2 receptor antagonists have been effective in urticaria, and
might reduce the histamine-mediated pulmonary cytokine storm in COVID-19. Can a
combination of Histamine-1 and Histamine-2 receptor blockers improve COVID-19 inpatient …
