Effects of high-frequency stimulation of the nucleus accumbens on the development and expression of ethanol sensitization in mice
The behavioural effects of high-frequency electrical stimulation (HFS) are often similar to the
effects of lesions, with the advantage of being reversible. The present study examined the
effects of HFS of the nucleus accumbens (NAc), an area that has been shown to be
important for sensitization to several psychostimulants, on the development and expression
of EtOH sensitization. Male DBA/2 mice received five biweekly injections of EtOH (2.2 g/kg,
intraperitoneally) or saline (SAL) immediately before assessments of locomotor activity …
effects of lesions, with the advantage of being reversible. The present study examined the
effects of HFS of the nucleus accumbens (NAc), an area that has been shown to be
important for sensitization to several psychostimulants, on the development and expression
of EtOH sensitization. Male DBA/2 mice received five biweekly injections of EtOH (2.2 g/kg,
intraperitoneally) or saline (SAL) immediately before assessments of locomotor activity …