Pulmonary arterial histologic lesions in patients with COPD with severe pulmonary hypertension
V Bunel, A Guyard, G Dauriat, C Danel, D Montani… - Chest, 2019 - Elsevier
Background The development of pulmonary hypertension (PH) during the course of COPD
is a well-known phenomenon, with the prevalence depending on the severity of airway
obstruction. When mean pulmonary pressure (mPAP) level at rest is≥ 35 mm Hg or≥ 25
mm Hg with low cardiac index, the term severe PH is used. For these patients, little is known
on the underlying histologic lesions. Our objective was to describe these lesions. Methods
From the explants of patients undergoing lung transplantation, we compared retrospectively …
is a well-known phenomenon, with the prevalence depending on the severity of airway
obstruction. When mean pulmonary pressure (mPAP) level at rest is≥ 35 mm Hg or≥ 25
mm Hg with low cardiac index, the term severe PH is used. For these patients, little is known
on the underlying histologic lesions. Our objective was to describe these lesions. Methods
From the explants of patients undergoing lung transplantation, we compared retrospectively …