[HTML][HTML] Thiazolides, a new class of anti-influenza molecules targeting viral hemagglutinin at the post-translational level
JF Rossignol, S La Frazia, L Chiappa, A Ciucci… - Journal of Biological …, 2009 - ASBMB
The emergence of highly contagious influenza A virus strains, such as the new H1N1 swine
influenza, represents a serious threat to global human health. Efforts to control emerging
influenza strains focus on surveillance and early diagnosis, as well as development of
effective vaccines and novel antiviral drugs. Herein we document the anti-influenza activity
of the anti-infective drug nitazoxanide and its active circulating-metabolite tizoxanide and
describe a class of second generation thiazolides effective against influenza A virus …
influenza, represents a serious threat to global human health. Efforts to control emerging
influenza strains focus on surveillance and early diagnosis, as well as development of
effective vaccines and novel antiviral drugs. Herein we document the anti-influenza activity
of the anti-infective drug nitazoxanide and its active circulating-metabolite tizoxanide and
describe a class of second generation thiazolides effective against influenza A virus …
