Piezo channel plays a part in retinal ganglion cell damage

W Morozumi, S Inagaki, Y Iwata, S Nakamura… - Experimental eye …, 2020 - Elsevier
Piezo channel is one of the mechanosensitive channels that senses pressure and shearing
stress. Previous reports show that Piezo channel is expressed in many tissues such as skin
and lung and they have many important roles. In addition, the mRNA of Piezo has been
detected in astrocytes in the optic nerve head of mice. However, it is not yet clear where
Piezo channel localize in eye and what kind of effects it have. Thus, the purpose of this study
was to determine the expression sites of Piezo channel in mouse eyes and effect of Piezo …