Iron status alters murine systemic lupus erythematosus
LM Leiter, KR Reuhl, SP Racis Jr, AR Sherman - The Journal of nutrition, 1995 - Elsevier
The effect of Fe status on murine systemic lupus erythematosus was investigated. Weanling
female MRL/MPJ-lpr/lpr mice (systemic lupus erythematosus strain) were fed diets with the
following levels (mg Fe/kg diet): 3 (severely deficient), 10 (moderately deficient), 35 (control)
and 250 (supplemented). A fifth group was pair fed the control diet in the amounts consumed
by the severely deficient group. C3H/Hej mice fed the same diets were used as nonlupus
controls. Anemia was more severe in severely deficient mice than in all other MRL groups …
female MRL/MPJ-lpr/lpr mice (systemic lupus erythematosus strain) were fed diets with the
following levels (mg Fe/kg diet): 3 (severely deficient), 10 (moderately deficient), 35 (control)
and 250 (supplemented). A fifth group was pair fed the control diet in the amounts consumed
by the severely deficient group. C3H/Hej mice fed the same diets were used as nonlupus
controls. Anemia was more severe in severely deficient mice than in all other MRL groups …