Sjögren's syndrome (SS) is a chronic autoimmune disease with broad clinical spectrum,
extending from benign exocrinopathy to severe systemic disease and lymphoma
development. The glandular and extraglandular dysfunction of SS is associated with
lymphocytic infiltrates that invade the epithelial structures of affected organs. The in-depth
study of autoimmune lesions in the minor salivary glands (MSG), which are the major target-
organ of SS responses, revealed that the lymphocytic infiltrates vary in severity and …