[HTML][HTML] The amino-terminal immunoglobulin-like domain of activated leukocyte cell adhesion molecule binds specifically to the membrane-proximal scavenger …
MA Bowen, J Bajorath, AW Siadak, B Modrell… - Journal of Biological …, 1996 - ASBMB
Activated leukocyte cell adhesion molecule (ALCAM) was recently identified as a ligand for
CD6, a signaling receptor expressed on T cells, a subset of B cells, and some cells in the
brain. Receptor-ligand binding assays, antibody blocking experiments, and examination of
the tissue distribution of these two cell surface proteins suggest that CD6-ALCAM
interactions play an important role in mediating the binding of thymocytes to thymic epithelial
cells and of T cells to activated leukocytes. Presently, the details of CD6-ALCAM interactions …
CD6, a signaling receptor expressed on T cells, a subset of B cells, and some cells in the
brain. Receptor-ligand binding assays, antibody blocking experiments, and examination of
the tissue distribution of these two cell surface proteins suggest that CD6-ALCAM
interactions play an important role in mediating the binding of thymocytes to thymic epithelial
cells and of T cells to activated leukocytes. Presently, the details of CD6-ALCAM interactions …