Change in iron transporter expression in human term placenta with different maternal iron status
YQ Li, H Yan, B Bai - European Journal of Obstetrics & Gynecology and …, 2008 - Elsevier
OBJECTIVES: To better understand the molecular mechanism of human placental iron
transfer, the protein and mRNA expression of iron transporters, transferrin receptor 1 (TfR1),
ferritin and ferroportin 1 (FP1) were examined simultaneously. STUDY DESIGN: Forty
pregnant women, 18 normal, 22 with anemia but all free from other medical conditions, were
chosen for the research and their iron status was determined before delivery. Forty human
term placentas were collected from these pregnant women with different iron status in the …
transfer, the protein and mRNA expression of iron transporters, transferrin receptor 1 (TfR1),
ferritin and ferroportin 1 (FP1) were examined simultaneously. STUDY DESIGN: Forty
pregnant women, 18 normal, 22 with anemia but all free from other medical conditions, were
chosen for the research and their iron status was determined before delivery. Forty human
term placentas were collected from these pregnant women with different iron status in the …