[HTML][HTML] Probable congenital SARS-CoV-2 infection in a neonate born to a woman with active SARS-CoV-2 infection

M Kirtsman, Y Diambomba, SM Poutanen… - Cmaj, 2020 - Can Med Assoc
M Kirtsman, Y Diambomba, SM Poutanen, AK Malinowski, E Vlachodimitropoulou, WT Parks…
Cmaj, 2020Can Med Assoc
Discussion Cases of suspected perinatal SARS-CoV-2 infection have been reported; 2, 3
however, in light of infrequent testing, the possibility of specimen contamination from
infected maternal sites, the questionable validity of serologic testing, 4 and a lack of
standardized definitions for congenital, intrapartum and postpartum transmission, more
evidence is needed to ascertain the route of transmission5 and to determine whether in
utero transmission has in fact occurred. Our case represents a probable case of congenital …
Discussion
Cases of suspected perinatal SARS-CoV-2 infection have been reported; 2, 3 however, in light of infrequent testing, the possibility of specimen contamination from infected maternal sites, the questionable validity of serologic testing, 4 and a lack of standardized definitions for congenital, intrapartum and postpartum transmission, more evidence is needed to ascertain the route of transmission5 and to determine whether in utero transmission has in fact occurred.
Our case represents a probable case of congenital SARS-CoV-2 infection in a liveborn neonate. Congenital infection is supported by the following findings: the neonate was not in contact with vaginal secretions; the membranes were intact before birth; and there was no skin-to-skin contact with the mother before collection of the first neonatal nasopharyngeal
Can Med Assoc