Association of BCG vaccination in childhood with subsequent cancer diagnoses: a 60-year follow-up of a clinical trial
NT Usher, S Chang, RS Howard, A Martinez… - JAMA network …, 2019 - jamanetwork.com
Importance The BCG vaccine is currently the only approved tuberculosis vaccine and is
widely administered worldwide, usually during infancy. Previous studies found increased
rates of lymphoma and leukemia in BCG-vaccinated populations. Objective To determine
whether BCG vaccination was associated with cancer rates in a secondary analysis of a
BCG vaccine trial. Design, Setting, and Participants Retrospective review (60-year follow-up)
of a clinical trial in which participants were assigned to the vaccine group by systematic …
widely administered worldwide, usually during infancy. Previous studies found increased
rates of lymphoma and leukemia in BCG-vaccinated populations. Objective To determine
whether BCG vaccination was associated with cancer rates in a secondary analysis of a
BCG vaccine trial. Design, Setting, and Participants Retrospective review (60-year follow-up)
of a clinical trial in which participants were assigned to the vaccine group by systematic …
