Angiopoietin-2 levels are associated with retinopathy and predict mortality in Malawian children with cerebral malaria: a retrospective case–control study
Objective: To investigate the relationship among the angiopoietin–Tie-2 system, retinopathy,
and mortality in children with cerebral malaria. Design: A case–control study of retinopathy-
positive vs. retinopathy-negative children with clinically defined cerebral malaria. Setting:
Queen Elizabeth Central Hospital in Blantyre, Malawi. Subjects: One hundred fifty-five
children presenting with severe malaria and meeting a strict definition of clinical cerebral
malaria (Blantyre Coma Score≤ 2, Plasmodium falciparum parasitemia, no other …
and mortality in children with cerebral malaria. Design: A case–control study of retinopathy-
positive vs. retinopathy-negative children with clinically defined cerebral malaria. Setting:
Queen Elizabeth Central Hospital in Blantyre, Malawi. Subjects: One hundred fifty-five
children presenting with severe malaria and meeting a strict definition of clinical cerebral
malaria (Blantyre Coma Score≤ 2, Plasmodium falciparum parasitemia, no other …