A comparison of the response of unstimulated and stimulated T-lymphocytes and fibroblasts from normal, xeroderma pigmentosum and trichothiodystrophy donors to …
CF Arlett, SA Harcourt, J Cole, MHL Green… - Mutation Research/DNA …, 1992 - Elsevier
Unstimulated T-lymphocytes from normal donors are significantly more sensitive to the lethal
effects of UV-C than either stimulated T-lymphocytes or fibroblasts as judged by colony-
forming ability. Data from other studies suggest that excision repair is more effective in
stimulated than unstimulated T-lymphocytes leading to the prediction that these differences
in survival should be minimal in cells established from excision defective donors. The
prediction was met with XP6BR, a donor of unknown complementation group. For 3 XP's …
effects of UV-C than either stimulated T-lymphocytes or fibroblasts as judged by colony-
forming ability. Data from other studies suggest that excision repair is more effective in
stimulated than unstimulated T-lymphocytes leading to the prediction that these differences
in survival should be minimal in cells established from excision defective donors. The
prediction was met with XP6BR, a donor of unknown complementation group. For 3 XP's …