BACKGROUND: Although anxiety disorders are the most prevalent psychiatric disorders, no
molecular biomarkers exist for their premorbid diagnosis, accurate patient
subcategorization, or treatment efficacy prediction. To unravel the neurobiological
underpinnings and identify candidate biomarkers and affected pathways for anxiety
disorders, we interrogated the mouse model of high anxiety-related behavior (HAB), normal
anxiety-related behavior (NAB), and low anxiety-related behavior (LAB) employing a …